Angiostatin Inhibits Coronary Angiogenesis During Impaired Production of Nitric Oxide
نویسندگان
چکیده
منابع مشابه
Angiostatin inhibits coronary angiogenesis during impaired production of nitric oxide.
BACKGROUND The in vivo mechanism by which inhibition of NO synthase impairs ischemia-induced coronary vascular growth is unknown. We hypothesized that production of the growth inhibitor angiostatin increases during decreased NO production, blunting angiogenesis and collateral growth. METHODS AND RESULTS Measurements were made in myocardial tissue or interstitial fluid (MIF) from dogs undergoi...
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ژورنال
عنوان ژورنال: Circulation
سال: 2002
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000015856.84385.e9